Which is the best way to protect a specimen from light when an Amber tube is not used?
Important NoteProtect from light. Show
Please call the Laboratory Customer Service Call Center at 616-774-7721 one hour prior to delivery and notify them that a Methotrexate Level has been sent to the Laboratory. Test Name AliasMethotrexate Blood Level | 8284 | MTX Interface Order Alias10205 Ordering InstructionsInpatients: Please contact your local inpatient pharmacy for information regarding appropriate timing for blood drug level orders, if needed. Please call the Laboratory Customer Service Call Center at 616-774-7721 ONE HOUR PRIOR to delivery and notify them that a Methotrexate Level has been sent to the Laboratory. Lab Call Center - Please notify Toxicology that a Methotrexate level is on the way. Icons & Photos Collection InstructionsSpecimen Collection: Blood Container(s): Red top (no additive) Preferred Volume to Collect: 3.0 mL Minimum Volume to Collect: 2.0 mL Neonate Volume to Collect: 2.0 mL Capillary collect ok? Yes Microtainer acceptable? Yes Collection Instructions:
Processing Instructions (Laboratory, Outpatient or Off-site collection)Processed Specimen: Serum Centrifuge/Spin: Yes Aliquot: Yes Processing Instructions:
Minimum plasma/serum volume: 1.0 mL Transport Temperature: Specimen StabilityAmbient: 36 hours Refrigerated: 7 days Laboratory Retention: 7 days Test FrequencyAvailable 24 hours, usual TAT 2 hours. The Methotrexate LC/MS assay will be run on a STAT basis with a turn around time of approximately 2 hours from the time the specimen is received. Reference RangeSerum concentrations of methotrexate are commonly monitored during high-dose therapy (>50 mg/m2) to identify the time at which active intervention by leucovorin rescue should be initiated. Criteria for serum concentrations indicative of a potential for toxicity after single-bolus, high-dose therapy are as follows: -Methotrexate >10 mcmol/L 24 hours after dose -Methotrexate >1 mcmol/L 48 hours after dose -Methotrexate >0.1 mcmol/L 72 hours after dose Methotrexate level results reported in micromolar (mcmol/L) units. To convert to mass (mcg/mL) units, multiply micromolar results by 0.454. To convert to mass (mcg/dL) units, multiply micromolar results by 45.4. Performing DepartmentTOXICOLOGY Performing Department Laboratory LocationSpectrum Health Regional Laboratory, Grand Rapids, MI MethodologyLiquid Chromatography-Mass Spectrometry This test was developed and its performance characteristics determined by Spectrum Health Toxicology Laboratory. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research. LOINCMethotrexate Lvl: 14836-1 Beaker LOINCMETHOTREXATE LEVEL: 14836-1 Mayo Access CodeSHO10205 Additional InformationAttn: Lab Central: Gold Top SST not acceptable Beaker NamesBeaker Procedure Name: METHOTREXATE LEVEL Beaker SynonymsNo synonym on file Beaker Collection and Specimen HandlingBEAKER COLLECTION: NO LIGHT+S/POPL/R BEAKER SHIPPING & HANDLING: Protect from light. Wrap tube lightly in paper towels or tinfoil. Plastic, amber pour-off tubes are acceptable to protect from light. Please call the Laboratory Customer Service Call Center at 616-774-7721 one hour prior to delivery and notify them that a Methotrexate Level has been sent to the Laboratory. Beaker Location, Container and TemperatureBW TOXICOLOGY: RED TOP TUBE R (Preferred)-Refrigerated How can you protect a specimen from light?Each specimen needs to be protected from light at all times. Please securely wrap the entire specimen in aluminum foil or paper towel or any other light protecting material.
What must be protected from light in a blood specimen?Certain blood specimens are photosensitive and should be protected from light. Bilirubin, beta-carotene, and porphyrins among others are such blood constituents that break down in the presence of light.
What should all bags transporting specimens have marked clearly?As you might already know, all specimen bags should be labeled with at least two identifiers: The patient's full name (which includes their last name, first name, and middle initial). The second patient identifier can include either the birthdate of the patient or a unique patient number, ID, or code.
Which laboratory test should be protected from light after blood collection?As such, laboratory practice mandates blood specimens for B12 and folate testing be protected from light after blood collection by wrapping the blood collection tube in aluminum foil or a commercially available light retardant wrap (eg, Coban, 3M, St.
|
